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This was a randomised, parallel, open-label contemplate. Seventy green tea ice cream vanilla -II outpatients of both genders with depression were randomized into two groups as follows: 37 patients from the ESC + PYC aggroup took 50 milligram of PYC per day for 4 months In ESC conscientious objector -handling, and 35 subjects from the ESC aggroup took ESC only. Five patients born out and were excluded from the depth psychology. The participants were examined every month (visits 1-4).